FUSION PROTEINS
Application 2526/KOLNP/2005 published 2006-12-01, filed 2005-12-07
The invention provides active therapeutic peptides fused to specific IgG4-Fc derivatives. These fusion proteins have an increased half-life, reduced half antibody formation, and reduced effector activity, while not being immunogenic. The fusion proteins are useful in treating human diseases as well as a variety of other conditions or disorders. (FIG.nil)
Applicant
ELI LILLY AND COMPANY
LILLY CORPORATE CENTER, INDIANAPOLIS, IN 46285, UNITED STATES OF AMERICA
Inventor
GLAESNER, WOLFGANG; MILLICAN, ROHN, LEE, JR.; TIAN, YU; TSCHANG, SHENG-HUNG; VICK, ANDREW, MARK
International Info
Classification: A61K 38/00
Publication Number: WO 04/110472
Application Date: 2004-06-10
Priority Information
60/477880 USA 2003-06-12
60/570908 USA 2004-05-13