SYNTHESIS OF VARIOUS SALTS OF CROSS-LINKED POLYALLYLAMINE POLYMER BY ION EXCHANGE METATHESIS

Application 262/CHE/2006 published 2006-12-22, filed 2006-02-20
The invention describe the method of preparing sevelamer Y soft salts from synthesis of cross linked polyallyl amine polymer by ion exchange process, the said method comprising suspending sevelamer hydrochloride in X molar solution of selected salt, MY or MY2 whose anion is be exchnged wherein M is an alkali an dalkali earth metal ion and Y is counter anion and the soft salts of cross linked polyallyl anine have improved phosphate absorption properties resulting in reduced damage within body and which improve patient tolerance and compliance, thereby improving the comfort level of patient and are relativly easy to manufacture.

Applicant

INDIAN INSTITUTE OF TECHNOLOGY
IIT P.O. CHENNAI 600 036, INDIA.

Inventor

International Info

Classification: A61K 31/785
Publication Number: