3', 3'-N-BIS-SUBSTITUTED MACROLIDE-LHRH ANTAGONISTS
Application IN/PCT/2000/00402/MUM published 2007-01-12, filed 2000-09-15
Disclosed are 3",3"-N-bisdesmethyl-3",3"-N-bis-substituted-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythromycin A derivatives of formula (I) which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, methods of using the compounds and the process of making the same. Disclosed are 3",3"-N-bisdesmethyl-3",3"-N-bis-substituted-6-O-methyl-11-deoxy-11,12 -cyclic carbamate erythromycin A derivatives of formula (I) which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, methods of using the compounds and the process of making the same.
Applicant
1)ABBOTT LABORATORIES
:100 ABBOTT PARK ROAD, ABBOTT PARK, ILLINOIS 600 064-6008, U.S.A.
Inventor
1)SAUER DARYL R
International Info
Classification: C07H 17/08, A61K 31/70
Publication Number: WO 99/50276 A1
Application Date: 1999-03-22
Priority Information
09/049,458 U.S.A. 1998-03-27