"IMIDAZOLE-4-CARBOXAMIDE DERIVATIVES PREPARATION AND USE THEREOF FOR TREATMENT OF OBESITY"
Application 612/DELNP/2004 published 2007-01-12, filed 2004-03-10
The present invention relates to novel compounds (I), their prodrugs, and the pharmaceutically acceptable salts as well as pharmaceutical compositions containing such compounds useful in treating certain metabolic diseases and diseases modulated by the inhibition of the enzyme malonyl-coenzyme A decarboxylase (malonyl-CoA decarboxylase, MCD). In particular, the invention relates to compounds and compositions and the methods for the prophylaxis, management and treatment of cardiovascular diseases, diabetes, acidosis, cancers, and obesity through the inhibition of malonyl-coenzyme A decarboxylase.
Applicant
1)BAYER PHARMACEUTICALS CORPORATION
:400 MORGAN LANE, WEST HAVEN, CT 06516, UNITED STATES OF AMETICA U.S.A.
Inventor
1)ROGER A. SMITH 2)STEPHEN J. O'CONNOR 3)STEPHAN-NICHOLAS WIRTZ 4)WAI C. WONG 5)SOONGYU CHOI 6)HAROLD C.E. KLUENDER 7)NING SU 8)WANG GAN 9)FURAHI ACHEBE 10)SHIHONG YING
International Info
Classification: A61K 31/42
Publication Number: WO 02/064136
Application Date: 2002-01-22
Priority Information
60/324,473 U.S.A. 2001-09-24