"INHIBITORS OF HISTONE DEACETYLASE"
Application 3153/DELNP/2004 published 2007-01-12, filed 2004-10-13
The invention concerns a compound of the formula (I); wherein Ring A is heterocyclyl; m is 0-4 and each Rl is a group such as hydroxy, halo, trifluoromethyl and cyano; Ring B is ring such as thienyl, thiadiazolyl, thiazolyl, pyrimidyl, pyrazinyl, pyridazinyl and pyridyl; R2 is halo and n is 0-2; and each R4 is a group such as hydroxy, halo, trifluoromethyl and cyano; p is 0-4; and R3 is amino or hydroxy; or pharmaceutically-acceplable salts or ;in-vivo-hydrolysable ester or amide thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical condions mediated by histone deacetylase.
Applicant
1)ASTRAZENCA AB
:S-151 85 SODERTALJE SWEDEN Sweden
Inventor
1)ELAINE SOPHIE ELIZABETH STOKERS 2)MICHAEL JAMES WARING 3)KEITH HOPKINSON GIBSON
International Info
Classification: A61K 31/44
Publication Number: WO 03/092686
Application Date: 2003-04-17
Priority Information
0209715.2 U.K. 2002-04-27