"NON-PEPTIDE GNRH AGENTS, METHODS AND INTERMEDIATES FOR THEIR PREPARATION"
Application IN/PCT/2001/00066/DEL published 2007-01-12, filed 2001-01-24
Non-peptide GnRH agents capable of inhibiting the effect of gonadotropin-releasing hormone are described. Such compounds and their pharmaceutically acceptable salts, multimers, prodrugs, and active metabolites are suitable for treating mammalian reproductive disorders and steroid hormone-dependent tumors as well as for regulating fertility, where suppression of gonadotropin release is indicated. Methods for synthesizing the compounds and intermediates useful in their preparation are also described.
Applicant
1)AGOURON PHARMACEUTICALS, INC.,
:CALIFORNIA CORPORATION, OF 10350 NORTH TORREY PINES ROAD, LA JOLLA, CALIFORNIA 92037, USA U.S.A.
Inventor
1)MARK BRIAN ANDERSON 2)HARESH N. VAZIR 3)DAVID ROBERT LUTHIN 4)GENEVIEVE DEGUZMAN PADERES 5)VED P. PATHAK 6)LANCE CHRISTOPHER CHRISTIE 7)YUFENG HONG 8)EILEEN VALENZUELA TOMPKINS 9)HAITAO LI, 10)JAMES FAUST
International Info
Classification: C07C
Publication Number: WO 00/20358
Application Date: 1999-08-20
Priority Information
60/097,520 U.S.A. 1998-08-02