"PURINE DERIVATIVES PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME"
Application IN/PCT/2001/01051/DEL published 2007-01-12, filed 2001-11-13
The invention concerns novel products of formula (I), wherein: Z represents -CH2-, -SO2 -CO-, -COO-, -CONH- or -(CH2)2-NR3-; n represents 0 or 1; R| represents hydrogen, aryl, -CH2-aryl, -SO2-aryl, -CO-aryl, heterocyclic, -CH2- heterocyclic, alkyl and -SO2-alkyl; R2 represents alkyl, cycloalkyl or heterocycle containing oxygen, sulphur or NR3; Y represents oxygen, sulphur or NR3; D1 and D2 are either selected among hydrogen, hydroxyl, alkyl, alkoxy and NHR5 or form =O, or =N-OR*; R3 represents hydrogen, alkyl or cycloalkyl; R* represents hydrogen, alkyl, cycloalkyl or aryl; R5 represents hydrogen, alkyl, cycloalkyl or -COOtbu; R6 represents hydrogen, halogen, hydroxyl, alkyl, alkoxy or NHR3; said products being all in isomeric forms and their salts, as medicines.
Applicant
1)AVENTIS PHARMA S.A.
:20 AVENUE RAYMOND ARON, F-92160 PUTEAUX,FRANCE France
Inventor
1)JEAN-LUC HAESSLEIN
International Info
Classification: C07D 473/16
Publication Number: WO 00/71543
Application Date: 2000-05-18
Priority Information
99/06456 France 1999-05-21