"SELECTED CGRP ANTAGONISTS, PROCESSES FOR PREPARING THEM AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS"
Application 1641/DELNP/2005 published 2007-01-19, filed 2005-04-21
The presnt invention relates to compounds of Formula (I), as antagonists of calcitonin gene-related peptide receptors ("CGRP-receptor"), pharmaceutical compositions comprising (I) them, methods for identifying them, methods of treatment using them and their use in therapy for treatment of neurogenic vasodilation, neurogenic inflammation, migraine and other headaches, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and other conditions the treatment of which can be effected by the antagonism of CGRP-receptors.
Applicant
1)BOEHRINGER INGELHEIM PHARMA GMBH & CO KG.,
:BINGER STRASSE 173, D-55216 INGELHEIM AM RHEIN, GERMANY Germany
Inventor
1)KLAUS RUDOLF, 2)STEPHAN GEORG MUELLER 3)DIRK STENKAMP 4)PHILIPP LUSTENBERGER 5)ALEXANDER DREYER 6)ECKHART BAUER 7)MARCUS SCHINDLER 8)KIRSTEN ARNDT 9)HENRI DOODS
International Info
Classification: C07D 487/14
Publication Number: WO 2004/037811
Application Date: 2003-10-23
Priority Information
102 50 082.7 Germany 2002-10-25