"NOVEL NEOMYCIN-PHOSPHOTRANSFERASE-GENES AND METHODS FOR THE SELECTION OF RECOMBINANT CELLS PRODUCING HIGH LEVELS OF A DESIRED GENE PRODUCT"
Application 2149/DELNP/2005 published 2007-01-19, filed 2005-05-20
The invention relates to novel modified neomycin phosphotransferase genes and the use thereof in a selection method for high-producing recombinant cells. The invention also relates to expression vectors containing a modified neomycin phosphoÂtransferase gene and a gene of interest in a functional bond with a heterologous promoter, and a method for producing heterologous gene products by using said expression vectors.
Applicant
1)BOEHRINGER INGELHEIM PHARMA GMBH & CO., KG,
:D-55216 INGELHEIM/RHEIN, GERMANY Germany
Inventor
1)BARBARA ENENKEL 2)KERSTIN SAUTTER 3)RALF OTTO 4)JURGEN FIEDER 5)KLAUS BERGEMANN
International Info
Classification: C12N 15/85
Publication Number: WO 2004/050884
Application Date: 2003-11-25
Priority Information
102 56 081.1 Germany 2002-11-29