"A novel process of Hepatitis A vaccine preparation”

Application 65/CHE/2004 published 2007-02-09, filed 2004-01-27
An Indian isolate of Hepatitis A virus -NIVIN97 has been isolated, adapted to tissue culture, characterized and further propagated using Vero and MRC-5 cell lines for vaccine preparation. The method involves the cell culture adaptation of the virus isolate from clinical sample (faecal) in BGMK cell line initially, characterization of the virus and further adaptation to Vera and MRC-5 cells, scale-up, inactivation and down stream processing method of the inactivated viral antigens for the preparation of an inactivated vaccine.

Applicant

Bharat Biotech International Limited & National Institute of Virology
Genome Valley Turkapalli Shameerpet Mandal Rangareddy District, & 20-A Dr. Ambedkar Road pune 411 001, Hyderabad, Andhra Pradesh, India

Inventor

International Info

Classification: G06F 19/00
Publication Number: