NON-AQUEOUS SINGLE PHASE VEHICLES AND FORMULATIONS UTILIZING SUCH VEHICLES
Application 1960/KOLNP/2005 published 2007-02-09, filed 2005-10-04
The present invention includes materials and methods for providing vehicles useful for providing drug formulations that address the potential drawbacks of known non-aqueous formulations. In particular, the present invention includes non-aqueous vehicles that are formed using a combination of polymer and solvent that results in a vehicle that is miscible in water. The non-aqueous vehicles facilitate the formulation of drug formulations that are stable over time, even when stored at, or exposed to, elevated temperatures. Moreover, the miscible vehicles of the present invention allow the preparation of drug formulations that work to reduce the occurrence of partial or complete occlusions of the delivery conduits included in delivery devices used to administer the drug formulations. (FIG). 1
Applicant
ALZA CORPORATION.,
1900 CHARLESTON ROAD, P.O.BOX 7210, MOUNTAIN VIEW, CA 94039-7210, USA.
Inventor
FEREIRA PAMELA DESJARDIN MICHAEL ROHLOFF CATHERINE BERRY STEPHEN
International Info
Classification: A61K 9/16, 47/10, 47/22, 47/32
Publication Number: WO 04/089335
Application Date: 2004-03-31
Priority Information
60/459,300 USA 2003-03-31