HYDROXAMID ACID DERIVATIVES AS HISTONE DEACETYLASE
Application 1877/CHENP/2005 published 2007-03-30, filed 2005-08-09
A compound having the following formula (I): wherein R 1< is N-containing heterocyclic ring optionally substituted with one or more suitable substituent(s), R 2? is hydroxyamino, R 3? is hydrogen or a suitable substituent, L 1? is -(CH?2#191)?n¿- (wherein n is an integer of 0 to 6) optionally substituted with one or more suitable substituent(s), wherein one or more methylene(s) may be replaced with suitable heteroatom(s), and L 2? is lower alkenylene, or a salt thereof. The compound is useful as a histone deacetylase inhibitor.
Applicant
1)Astellas Pharma Inc
:3-11, Nihonbashi-Honcho 2-chome, Chuo-ku, Tokyo 103-8411 Japan
Inventor
1)URANO, Yasuharu 2)SATOH, Shigeki 3)ISHIBASHI, Naoki 4)KAMIJO, Kazunori No of Pages : 239 No of Claims : 20
International Info
Classification: C07D 235/16
Publication Number: WO/2004/063169
Application Date: 2004-01-13
Priority Information
2003-900116 Australia 2003-01-13