METHODS OF DIAGNOSING AND TREATING PRE-ECLAMPSIA OR ECLAMPSLA

Application 218/CHENP/2005 published 2007-03-30, filed 2005-02-18
Disclosed herein are methods for diagnosing pre-eclampsia and eclampsia. Also disclosed herein are methods for treating pre-eclampsia and eclampsia using compounds that increase VEGF or PIGF levels or compounds that decrease sFlt-1 levels. Compounds that inhibit the binding of VEGF or PIGF to SFltl - are also disclosed herein for the treatment of pre-eclampsia or eclampsia

Applicant

1)BETH ISRAEL DEACONESS MEDICAL CENTER
:330 Brookline Avenue, Boston, MA 02215 U.S.A.

Inventor

1)KARUMANCHI, S., Ananth 2)MAYNARD, Sharon 3)SUKHATME, Vikas, P. No of Pages : 90 No of Claims : 80

International Info

Classification: A61K 31/522
Publication Number: WO/04/008946
Application Date: 2003-07-21

Priority Information

60/397,481 U.S.A. 2002-07-19