BigPatents India

The invention concerns amide derivatives of Formula (la) wherein X is - NHCO- or -CONH-; m is 0-3; R1 is a group such as hydroxy, halogeno, trifluoromethyl, cyano, mercapto, nitro, amino, carboxy and carbamoyl; n is 0-2; R2 is a group such as hydroxy, halogeno, trifluoromethyl, cyano, mercapto, nitro, amino and carboxy; R3 is hydrogen, halogeno, (l-6C)alkyl or (l-6C)alkoxy; q is 0-4; and Q is a group such as aryl, aryloxy, aryl-(l-6C)alkoxy, arylamino and N-(l-6C)alkyl-arylamino; or pharmaceutically-acceptable salts or in-vivo-cleavable esters thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.