"THLEROGENIC PEPTIDES FROM MYELIN BASIC PROTEIN"

Application 2044/DELNP/2004 published 2007-04-13, filed 2004-07-15
There is provided a peptide which is capable of binding to an MHC class I or II molecule without further processing (i.e. an apitope) which comprises a portion of the region (131-158) of myelin basic protein, in particular there is provided an apitope which is selected from the following myelin basic protein peptides: (134-148, 135-149, 136-150, 137-151, 138-152, 139-153, 140-154). There is also provided the use of such a peptide in a pharmaceutical composition and a method to treat and/or prevent a disease using such a peptide.

Applicant

1)APITOPE TECHNOLOGY [BRISTOL] LIMITED,
:UNIVERSITY OF BRISTOL, DEPARTMENT OF PATHOLOGY AND MICROBILOLGY, UNIVERSITY WALK, BRISTOL BS8 1TD, UNITED KINGDOM, U.K.

Inventor

1)DAVID CAMERON WRAITH, 2)HEATHER BARBARA STREETER, 3)FRANCES MARY PONSFORD, 4)GRAZIELLA MAZZA, No of Pages : 20 No of Claims : 8

International Info

Classification: C07K7/00
Publication Number: WO 03/064464 A1
Application Date: 2003-01-30

Priority Information

0202399-2 U.K. 2002-02-01