"POLYMER CONJUGATES OF MUTATED NEUBLASTIN"
Application 3372/DELNP/2005 published 2007-04-13, filed 2005-07-28
A dimer comprising a mutated neublastin polypeptide coupled ID a polymer is disclosed. Such dimers exhibit prolonged bioavailability and, in preferred embodiments, prolonged biological activity relative to wild-type forms of neublastin.
Applicant
1)BIOGEN IDEC MA INC.
:14 CAMBRIDGE CENTER, CAMBRIDGE, MASSACHUSETTS 02142, USA U.S.A.
Inventor
1)DINAH WEN-YEE SAH 2)R. BLAKE PEPINKSY 3)PAULA ANN BORIACK-SJODIN 4)STEPHAN S. MILLER 5)ANTHONY ROSSOMANDO No of Pages : 73 No of Claims : 34
International Info
Classification: A61K
Publication Number: WO 2004/069176
Application Date: 2004-02-02
Priority Information
10/356,264 U.S.A. 2003-01-31