CEPHEM COMPOUNDS
Application 823/KOLNP/2006 published 2007-04-13, filed 2006-04-04
The present invention relates to a compound of the formula [I]: wherein R1 is lower alkyl or hydroxy (lower) alkyl, and R2 is hydrogen or amino protecting group, or R1 and R2 are bonded together and form lower alkylene; R3 is - A-R6 wherein A is bond, -NHCO-(CH2CO)n-, lower alkylene, -NH-CO-CO- or the like, and R6 is (a) ou (b) wherein R7, R8, R9 and R10 are independently amino, guanidino, amidino or the like; R4 is carboxy or protected carboxy; and R5 is amino or protected amino, or a pharmaceutically acceptable salt thereof, a process for preparing a compound of the formula [I], and a pharmaceutical composition comprising a compound of the formula [I] in admixture with a pharmaceutically acceptable carrier.
Applicant
1)ASTELLAS PHARMA INC.
:3-11, NIHONBASHI-HONCHO 2-CHOME, CHUO-KU, TOKYO 103-8411 Japan 2)WAKUNAGA PHARMACEUTICAL CO., LTD.
Inventor
1)YAMANAKA TOSHIO 2)MURANO KENJI 3)TODA AYAKO 4)OHKI HIDENORI 5)OOGAKI MASARU 6)OKUDA SHINYA 7)KAWABATA KOHJI 8)INOUE SATOSHI 9)ITOH KENJI 10)SATO KENJI 11)MISUMI KEIJI No of Pages : 105 No of Claims : 18
International Info
Classification: A61K31/546; C07D501/00
Publication Number: WO 2005/027909
Application Date: 2004-09-17
Priority Information
2003905084 Australia 2003-09-18