NEW MANDELIC ACID DERIVATIVES THEIR USE AS THROMBIN INHIBITORS

Application 99/MUMNP/2004 published 2006-02-03, filed 2004-02-10
There is provided a compound of formula (I) and pharmaceutically-acceptable derivatives (including prodrugs) thereof, which compound and derivatives are useful as, or are useful as prodrugs of, competitive inhibitors of trypsin-like proteases, such as thrombin, and thus, in particular, in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants. Drawing NIL Sheets. Total Pages: 63

Applicant

ASTRAZENECA AB
S-151 85 SODERTAIJE, SWEDEN

Inventor

1. TORD INGHARDT 2. ANDERS JOHANSSON 3. ARNE SVENSSON

International Info

Classification: C07D 205/04
Publication Number: WO 03/018551 A1
Application Date: 2002-08-30

Priority Information

0102921.4 SWEDEN 2001-08-30