AUTOMATED MEDIA OPTIMIZATION TECHNOLOGY
Application 1992/KOLNP/2006 published 2007-05-18, filed 2006-07-14
An automated system and method for identifying agents capable of eliciting a phenotypic change in a cell-type. The method includes the steps of providing a statistical design including generic factor names, factor levels and experimental runs, and utilizing a software program to generate a computer representation of the statistical design by automatically mapping the identities of the agents to the generic factor names, concentrations or amounts of the agents to the factor levels, and the locations of the receptacles to the experimental runs. The method also includes placing different mixtures of single agents, such as peptones, into receptacles in the array based on the computer representation of the statistical design, contacting the placed mixtures with cells, acquiring experimental data from the contacted cells, and utilizing a processor including an algorithm for comparing the acquired data with the statistical design to identify peptone combinations and concentrations that optimize cell culture conditions.
Applicant
BECTON DICKINSON
:1 Becton Drive Franklin Lakes NJ 07417-1880 U.S.A.
Inventor
1)HAALAND PERRY D 2)CHANEY BRYCE N 3)HOLDREAD STACY D No of Pages : 74 No of Claims : 20
International Info
Classification: G01N33/48; G01N33/50
Publication Number: WO 2005/070037
Application Date: 2005-01-06