"METHOD OF STABILIZING PROTEINS"

Application 6969/DELNP/2006 published 2007-06-22, filed 2006-11-21
A method of preparing a stabilized bulk solution of a monomeric protein is described, which consists in providing a bulk of monomeric protein in a buffer solution and adding an excipient to the bulk, wherein the excipient is selected from the group consisting of bacteriostatic agents, surfactants, isotonicity agents, arnino acids, antioxidants and combinations thereof. Preferably the monomeric protein is IFN-beta.

Applicant

1)ARES TRADING S.A.,
:ZONE INDUSTRIELLE DE I' OURIETTAZ,CH-1170 AUBONNE,SWITZERLAND. Switzerland

Inventor

1)JABER AMER

International Info

Classification: A61K 38/21
Publication Number: WO 2005/117948 A1
Application Date: 2005-05-27

Priority Information

04076627.1 EUROPEAN UNION 2004-06-01