"PROCESS FOR THE PREPARATION OF FLUDARABINE PHOSPHATE."

Application 2005/DELNP/2006 published 2007-07-13, filed 2006-04-12
A description is given of a process for the preparation of 9-beta-D-arabinofuranosyl-2-fluoroadenine-5'-phosphate starting from 9-beta-D-arabinofuranosyl-2-fluoroadenine by reaction with a mixture composed of triethyl phosphate and phosphorus oxychloride and in accordance with a work-up which provides for the use of toluene.

Applicant

1)ADORKEM TECHNOLOGY SPA
:Via L. Da Vinci, 28, I-24062 Costa Volpino, ITALY. Italy

Inventor

1)COTTICELLI, GIOVANNI 2)VERZOLA, Barbara

International Info

Classification: C07H 19/00
Publication Number: WO2005/040183
Application Date: 2004-10-13

Priority Information

MI2003A001994 Italy 2003-10-15