CHEMO-ENZYMATIC PROCESS FOR PREPARING ESCITALOPRAM
Application 5820/DELNP/2006 published 2007-07-13, filed 2006-10-06
A process is described for preparing the intermediate for synthesizing escitalopram and the pharmaceutically acceptable salts thereof from 4-(4-dimethylamino)-1 -(4 "-fluorophenyl)-1 -(hydroxybutyl)-3-(acyloxymethyl) benzonitrile which, by means of enzymatic enantiomeric resolution, is synthesized into one of the enantiomers thereof.
Applicant
1)ADORKEM TECHNOLOGY SPA
:VIA L. DA VINCI,28,I-24062 COSTA VOLPINO
Inventor
1)COTTICELLI GIOVANNI 2)ROCCHIETTI SILVIA 3)TERRENI MARCO 4)PREGNOLATO MASSIMO 5)SALVETTI RAUL
International Info
Classification: C12P 41/00
Publication Number: WO2005/098018
Application Date: 2005-04-07
Priority Information
MI2004A000717 Italy 2004-04-09