PIPERIDINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF
Application 797/KOLNP/2007 published 2007-07-13, filed 2007-03-06
The piperidine derivative of the present invention in which the 4-position of the piperidine ring is bonded, via vinylene, to a mono-substituted (-R1) or unsubstituted benzene ring and the 1-position of the piperidine ring has an acyl group [-C(=O)-R4], or a pharmaceutically acceptable salt thereof has an excellent sodium channel inhibition action and an excellent analgesic action and shows a high analgesic effect particularly to neurogenic pain. The present compound is useful as a sodium channel inhibitor of low side effect
Applicant
1)ASTELLAS PHARMA INC
:A CORPORATION ORGANIZED UNDER THE LAWS OF JAPAN 3-11, NIHONBASHI-HONCHO 2-CHOME, CHUO-KU, TOKYO 103-8411, Japan 2)KOTOBUKI PHARMACEUTICAL CO., LTD.
Inventor
1)KAZUMI KIKUCHI 2)JIRO FUJIYASU 3)TOSHIHIRO WATANABE 4)YUKINORI NAGAKURA 5)HIROSHI TOMIYAMA 6)MOTOHARU SONEGAWA 7)KAZUO TOKUZAKI 8)YOSHINORI IWAI
International Info
Classification: C07D 211/16
Publication Number: WO 2006/025471
Application Date: 2005-08-31
Priority Information
2004-254478 Japan 2004-09-01