METHOD OF SYNTHESIZING KEY INTERMEDIATES FOR THE PRODUCTION OF CAMPTOTHECIN DERIVATIVES
Application 1053/CHE/2005 published 2007-07-20, filed 2005-08-03
The present invention discloses a process for efficient production of 2-amino-5-hydroxypropiophenone corresponding to the AB ring part of camptothecin (CPT) skelton, which is a key intermediate useful for the total synthesis of camptothecin analogs including 7-Ethyl-10-hydroxycamptothecin and novel intermediates thereof.
Applicant
1)AVRA LABORATORIES PVT. LTD.
:AVRA HOUSE 54 SAI ENCLAVE HABSIGUDA HYDERABAD-500 007 ANDHRA PRADESH, INDIA Andhra Pradesh India
Inventor
1)RAO, RAMAKRISHNA 2)ALLA, VENKATA RAMA RAO
International Info
Classification: C07D 491/22