INDOLE ACETIC ACIDS EXHIBITING CRTH2 RECEPTOR ANTAGONISM AND USES THEREOF.

Application 1395/KOLNP/2007 published 2007-07-20, filed 2007-04-19
The invention relates to indole acetic acid compounds which function as antagonists of the CRTH2 receptor. The mention also relates to the use of these compounds to inhibit the binding of prostaglandin D2 and its metabolites or certain thromboxane metabolites to the CRTH2 receptor and to treat disorders responsive to such inhibition.

Applicant

1)ATHERSYS, INC.
:3201, CARNEGIE AVENUE, CLEVELAND, OHIO 44115-2634, UNITED STATES OF AMERICA U.S.A.

Inventor

1)BENNANI, YOUSSEF L. 2)TUMEY, L. NATHAN 3)GLEASON, ELIZABETH ANN 4)ROBARGE, MICHAEL JOSEPH

International Info

Classification: C07D 417/04
Publication Number: WO 2006/034419
Application Date: 2005-09-21

Priority Information

60/611,316 U.S.A. 2004-09-21