CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS WITH ENHANCED EFFICACY

Application 2076/KOLNP/2005 published 2007-07-27, filed 2005-10-21
Compounds that interact with the CXCR4 receptor are described. The compounds are useful in treating example, HIV infection and inflammatory condition such as rheumatoid arthritis, as well as asthma or cancer, and are useful in methods to Elevate progenitor and stem cell counts as well as elevate white blood cell count.

Applicant

1)ANORMED INC.
:#200-20353 64TH AVENUE, LANGLEY, BRITISH COLUMBIA V2Y IN5 CANADA

Inventor

1)BRIDGER GARY J 2)MCEACHERN ERNEST J 3)SKERLJ RENATO 4)SCHOLS DOMINIQUE 5)BAIRD LAN 6)KALLER AI 7)HARWIG CURTIS 8)ZHU YONGBAO 9)CHEN GANG 10)SKUPPINSKA KRYSTYNA 11)METZ MARKUS

International Info

Classification: A61K 31/40
Publication Number: WO 2004/093817
Application Date: 2004-04-22

Priority Information

60/464,858 U.S.A. 2003-04-22