"NOVEL AMYLIN FAMILY POLYPEPTIDE-6

Application 2203/DELNP/2007 published 2007-08-03, filed 2007-03-21
The present invention relates to Amylin Family Polypeptide-6 (AFP-6) analogs, which include derivatives and fragments, related nucleic acids, expression constructs, host cells, and processes for recombinant production of the AFP-6 analogs. The AFP-6 analogs of the invention include one or more amino acid sequence modifications. In addition, methods and compositions are disclosed to treat and prevent conditions such as metabolic and cardiovascular disorders, e.g., obesity, diabetes, metabolic syndrome, myocardial ischemia, and increased cardiovascular risk.

Applicant

1)AMYLIN PHARMACEUTICALS,INC.
:9360 TOWNE CENTRE DRIVE SAN DIEGO, CALIFORNIA 92121 USA U.S.A.

Inventor

1)ERICKSON MARY 2)SRIVASTAVA VED 3)MCQUAID SARAH 4)YOUNG ANDREW 5)PITTNER RICHARD 6)GHOSH SOUMITRA

International Info

Classification: C07K 14/575
Publication Number: WO 2006/042242
Application Date: 2005-10-11

Priority Information

60/617,468 U.S.A. 2004-10-08