"SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF THEIR USE"

Application 2347/DELNP/2006 published 2007-08-03, filed 2006-04-27
Spirocyclic heterocyclic derivatives, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the spirocyclic heterocyclic derivatives are ligands of the &dgr; opioid receptor and may be useful, inter alia, for treating and/or preventing pain, anxiety, gastrointestinal disorders, and other &dgr; opioid receptor-mediated conditions.

Applicant

1)ADOLOR CORPORATION
:700 PENNSYLVANIA DRIVE, EXTON, PENNSYLVANIA 19341, USA, U.S.A.

Inventor

1)ROLAND E. DOLLE 2)BETRAND LE BOURDONNEC 3)CHRISTOPHER W. AJELLO 4)MINGHUA GU, 5)GUO-HUA CHU 6)PAUL ASTON TUTHILL,SR. 7)LARA K. LEISTER 8)Q. JEAN ZHOU

International Info

Classification: C07D
Publication Number: WO 2005/033073
Application Date: 2004-10-01

Priority Information

60/507,864 U.S.A. 2003-10-01