"INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME"

Application 5145/DELNP/2007 published 2007-08-17, filed 2007-07-03
The present invention relates to compounds that are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.

Applicant

1)ABBOTT LABORATORIES
:100 ABBOTT PARK ROAD, ABBOTT PARK, ILLINOIS 60064-6008 USA. U.S.A.

Inventor

1)ROHDE JEFFREY J, 2)SHUAI QI 3)LINK JAMES T., 4)PATEL JYOTI R., 5)DINGES JURGEN 6)SORENSEN BRYAN K., 7)YONG HONG 8)YEH VINCE S., 9)KURUKULASURIYA RAVI

International Info

Classification: C07C 233/65
Publication Number: WO 2006/074330
Application Date: 2006-01-05

Priority Information

60/641,496 U.S.A. 2005-01-05