"SYNTHESIS PROCESS FOR 2-

Application 1812/DELNP/2007 published 2007-08-17, filed 2007-03-08
A highly advantageous process for the preparation of 2-(3 -hydroxy-1-adamantyl) 2-oxoacetic acid or a salt thereof is described. The process comprises subjecting 1-acetyl 3-hydroxyadamantane to liquid phase oxidation with permanganate to produce 2-(3-hydroxy-l-adamantyl)-2-oxoacetic acid or a salt thereof, with acidification to form the free acid when appropriate.

Applicant

1)ALBEMARLE CORPORATION
:451 FLORIDA STREET, BATON ROUGE, LOUISIANA 70801-1765, USA U.S.A.

Inventor

1)ERIC L. WILLIAMS

International Info

Classification: C07C 51/16
Publication Number: WO 2006/034175
Application Date: 2005-09-16

Priority Information

60/610,893 U.S.A. 2004-09-17