DERIVATIVES OF ARYLSULFONAMIDO-SUBSTITUTED HYDROXAMIC ACID AS MATRIX METALLOPROTEINASES INHIBITORS

Application 945/CHENP/2007 published 2007-08-24, filed 2007-03-05
Described herein are derivatives of arylsulfonamido-substituted hydroxamic acid of formula (I) having good solubility in water and inhibitory activity of matrix metalloproteinases, useful for the preparation of pharmaceutical compositions for the treatment of diseases associated to a pathologic activity and/or an over-expression of metalloproteinases, and of cosmetic preparations having anti-ageing properties in particular for hair and skin.

Applicant

1)ABIOGEN PHARMA S.P.A.
:VIA MEUCCI 36, I-56014 LOC, OSPEDALETTO, ITALY Italy

Inventor

1)BERTINI, IVANO 2)FRAGAI, MARCO 3)LO CONTE, MAURO 4)LUCHINAT, CLAUDIO 5)NATIVI, CRTISTINA 6)VENTURI, CHIARA,

International Info

Classification: C07C 317/14
Publication Number: WO 2006/013193 A2
Application Date: 2005-07-29

Priority Information

FI2004A000174 Italy 2004-08-03