"BACTERIAL PACKING STRAINS USEFUL FOR GENERATION AND PRODUCTION OF RECOMBINANT DOUBLE STRANDED RNA NUCLEOCAPSIDS"
Application 3689/DELNP/2007 published 2007-08-24, filed 2007-05-17
Bacterial packaging strains useful for generating recombinant double-stranded RNA nucleocapsids (rdsRNs) are provided. The packaging strains are useful for the production of RNA encoding vaccine antigens, bioactive proteins, immunoregulatory proteins, antisense RNAs. and catalytic RNAs in eukaryotic cells or tissues. Recombinant ssRNA is introduced into the strains and packaged to form rdsRNs de novo.
Applicant
1)AERAS GLOBAL TB VACCINE FOUNDATION
:7500 OLD GEORGETOWN ROAD, SUITE 800, BETHESDA, MD 20814, USA U.S.A.
Inventor
1)DAVID MICHAEL HONE 2)JOHN FULKERSON 3)JERALD C.SADOFF 4)DAVID ONYABE 5)MICHELE STONE
International Info
Classification: A61K 39/02
Publication Number: WO 2006/060257
Application Date: 2005-11-23
Priority Information
10/999,074 U.S.A. 2004-11-30