METHOD FOR THE IDENTIFICATION OF LIGANDS
Application 214/KOLNP/2005 published 2006-03-03, filed 2005-02-17
The present invention relates generally to a method of identifying ligands that modulate protein-protein interactions. More particularly, the present invention relates to methods of determining agonists or antagonists of a co-regulator dependent target molecule based on the ability to modify the stability of the target molecule in a tissue-selective manner. (FIG. -)
Applicant
3-DIMENSIONAL PHARMACEUTICALS INC
EAGLEVIEW CORPORATE CENTER 665 STOCKTON DRIVE SUITE 104 EXTON PA 19341 USA
Inventor
1. BONE ROGER F 2. RENTZEPERIS DIONISIOS 3. ASKARI HOSSEIN 4. SPRINGER BARRY A
International Info
Classification: G01N 33/53,33/567
Publication Number: WO 04/010108 A3
Application Date: 2003-07-23
Priority Information
60/398,023 US 2002-07-24