COMPOUNDS HAVING INHIBITIVE ACTIVITY OF PHOSPHATIDYLINOSITOL 3-KINASE AND METHODS OF USE THEREOF

Application 4/MUMNP/2006 published 2007-09-14, filed 2006-01-02
Compounds inhibiting phosphatidylinositol 3-kinase (PI 3-K) activities and methods of preparing and using thereof in treating diseases are disclosed. Compounds inhibiting PI 3-K activity and methods of using PI 3-K inhibitory compounds to inhibit cancer cell grwoth or to treat disorders of immunity and inflammation, in which PI 3-K plays a role in leukocyte function are also provided.

Applicant

1) ZENTARIS GMBH
: Weismüllerstrasse 50, D-60314 Frankfurt, GERMANY

Inventor

1) DREES, BETH, E. 2) CHAKRAVARTY, LEENA 3) PRESTWICH, GLENN, D. 4) DORMAN, GYORGY 5) KAVECZ, MARIANN 6) LUKACS, ANDRAS 7) URGE, LASZLO 8) DARVAS, FERENC 9) RZEPECKI, PIOTR, W. 10) FERGUSON, COLIN, G.

International Info

Classification: A61K31/437
Publication Number: WO/2005/016245
Application Date: 2004-06-14

Priority Information

60/478,221 USA 2003-06-13