“ Novel molecules to develop drug for the treatment of osteoporosis“
Application 497/DELNP/2004 published 2006-03-10, filed 2004-02-27
This invention relates to a novel class of acidic amino acid/dicarboxylic acid derivatives (sulfonic acid/sulfate derivatives of naturally occurring amino acids and their amides) useful as inhibitors of osteoclastogenesis. The invention also provides methods of using the novel class of acidic amino acid/dicarboxylic acid derivatives of the general formula Z-OC-CRn1Rn2-COOZ, wherein n1=n2= 1 to 8 and Z=OH or NH2 and its derivatives for inhibition of osteoclastogenesis.
Applicant
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
Rafi Marg, New Delhi-110 001 India
Inventor
1. Kanury Venkata Subba Rao 2. Mohan Ramachandran Wani 3. Venkatasamy Manivel 4. Parameswaren Perunninakulath Subrayan 5. Vinod Kumar Singh 6. Ramasamy Vijaya Anand 7. Ehrlich Desa 8. Gyan Chandra Mishra 9. Anil Chatterji
International Info
Classification: A61K 35/78
Publication Number: WO 2005/037774
Application Date: 2003-12-31