METHOD FOR PRODUCING OPTICALLY ACTIVE 2-METHYL-ALKANOLS
Application 1777/CHENP/2007 published 2007-09-28, filed 2007-04-30
The invention relates to a method for producing optically active 2-methylalkane-1-ol of general formula (III), comprising the following steps: (i) carbonyl-selective reduction of 2-methylalk-2-en-1-al of general formula (I) to 2-methylalk-2-en-1-ol of general formula (II), (ii) enantioselective hydration of 2-methylalk-2-en-1-ol to give the compound of general formula (III), (iii) increasing the optical yield of the optically active 2-methylalkane-1-ol (III) obtained in step (ii) by way of a lipase-catalyzed acylation reaction, whereby R represents C1-C10 alkyl.
Applicant
1)BASF AKTIENGESELLSCHAFT
:D-67056 Ludwigshafen Germany
Inventor
1)JÄKEL, Christoph 2)HEYDRICH, Gunnar 3)STÜRMER, Rainer 4)PACIELLO, Rocco
International Info
Classification: C07C 29/141
Publication Number: WO/2006/034812
Application Date: 2005-09-22
Priority Information
10 2004 047 836.8 Germany 2004-09-29