A NOVEL PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-CYANOQUINOLINES AS PROTEIN TYROSINE KINASES INHIBITORS
Application IN/PCT/2001/00531-A published 2006-03-10, filed 2001-05-22
This invention provides compounds of formula (1), wherein R1, G1, G2, R4, Z, X and n are defined herein, or a pharmaceutically acceptable salt thereof, which are useful as antineoplastic agents and in the treatment of polycystic kidney disease and a process for the preparation of this compound. (FIG. - Nil)
Applicant
AMERICAN CYNAMID COMPANY
FIVE GIRALDA FARMS,MADISON, NJ 07940-0874 USA
Inventor
WISSNER ALLAN TSOU HWEI-RU BERGER DAN MARRTEN FLOYD MIDDLETON BRAWNER JR. HAMANN PHILIP ROSS ZHANG NAN FORST PHILIP
International Info
Classification: C07D 401/12
Publication Number: WO 00/18740
Application Date: 1999-09-22
Priority Information
09/162,289 USA 1998-09-29