: A PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-CYANOQUINOLINES AS PROTEIN TYROSINE KINASES INHIBITORS
Application IN/PCT/2001/00531-B published 2006-03-10, filed 2001-05-22
This invention provides compounds of formula (1) wherein R1, G1, G2, R4, Z, X and n are defined herein, or a pharmaceutically acceptable salt thereof, which are use full as antineoplastic agents and in the treatment of polycystic kidney disease and a process for the preparation of this compound. (FIG.Nil)
Applicant
AMERICAN CYANAMID COMPANY.,
FIVE GIRALDA FARMS, MADISON, NEW JERSEY 07940-0874, USA.
Inventor
WISSNER ALLAN TSOU-HWEI-RU BERGER DAN MAARTEN FLOYD MIDDLETONBRAWNER JR HAMANN PHILIP ROSS ZHANG NAN
International Info
Classification: C07D 401/12 A61K 31/47
Publication Number: WO 00/18761
Application Date: 1999-09-22
Priority Information
09/162,802 USA 1998-09-29