"PROCESS FOR PREPARATION OF COMPOUNDS FOR TREATMENT OF CANCERS"
Application 7004/DELNP/2007 published 2007-09-28, filed 2007-09-10
The invention relates to chemical processes and intermediates useful in the manufacture of the quinazoline derivative 4 (3" chloro 4" fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline. In particular, the invention relates to processes for the manufacture of 7-methoxy-6-(3-morpholinopropoxy)-3,4-dihydroquinazolin-4-one of Formula (II) and 4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile of Formula (III) and their use in the manufacture of said quinazoline derivative.
Applicant
1)ASTRAZENECA AB
:S-151 85 SODERTALJE, SWEDEN. Sweden
Inventor
1)JOHN PETER GILDAY 2)DAVID MOODY
International Info
Classification: C07D 239/88, C07D 239/94
Publication Number: WO 2004/024703
Application Date: 2003-09-09
Priority Information
0221245.4 U.K. 2002-09-13