BORRELIDIN PRODUCING POLYKETIDE SYNTHASE AND ITS USE
Application 733/KOLNP/2005 published 2006-03-24, filed 2005-04-26
The present invention relates to the biosynthesis of polyketides and derives from the cloning of nucleic acids encoding a polyketide synthase and other associated proteins involved in the synthesis of the polyketide borrelidin. Materials and methods including enzyme systems, nucleic acids, vectors and cells are provided for the preparation of polyketides including borrelidin and analogues and derivatives thereof. Novel polyketide molecules are also provided. (FIG. - 1)
Applicant
BIOTICA TECHNOLOGY LTD
CHESTERFORD RESEARCH PARK LITTLE CHESTERFORD NR SAFFRON WALDEN ESSEX CB10,1XL GB
Inventor
1. BRANA ALFREDO FERNANDEZ 2. LEADLAY PETER FRANCIS 3. MARTIN CHRISTINE JANET 4. MENDEZ CARMEN 5. MOSS STEVEN JAMES 6. OLANIO CARLOS 7. OLIYNYK MARKIYAN 8. SALAS JOSE ANTONIO 9. SANCHEZ CESAR 10. WILKINSON BARRIE
International Info
Classification: C12N 15/52,C07D 313/00,C12P 17/08,C12R 1/465
Publication Number: WO 04/058976 A3
Application Date: 2003-12-24
Priority Information
0230217.2 GB 2002-12-27