STABLE COATED MICROCAPSULES

Application 201/KOLNP/2004 published 2006-04-07, filed 2004-02-16
The present invention provides a process for the preparation of a microencapsulated composition containing lipophilic compounds comprising of the following steps:(i) Particle size reduction of the lipophilic compound in the presence of a surface active agent;(ii) Preparing a solution of alkali metal alginate.(iii) Combining the solutions of step (i) and step (ii).(iv) Adding dropwise the solution obtained from stage (iii) to a solution containing Ca2+, obtaining beadlets, and removing the formed beadlets from said solution;(v) Rinsing the beadlets with an acidic solution and drying;(vi) Coating the beadlets obtained from step (v) to obtain the microcapsules.The present invention, in one aspect, relates to a microencapsulated composition comprising of one or more lipophilic compound enveloped by a surfactant which is encapsulated in an alginate matrix and further coated with an outer coating, wherein the particle size of the lipophilic substance is not greater than 20 ?m (FIG.nil).

Applicant

BIO-DAR LTD
YAVNE TECHNOLOGY PARK, P.O.BOX 344, 81103 YAVNR, ISRAEL.

Inventor

BLATT YOAV PINTO RIKA SAFRONCHIK OLEG SEDLOV TANYA ZELKHA MORRIS

International Info

Classification: B01J 13/02
Publication Number: WO 03/018186
Application Date: 2002-08-21

Priority Information

09/935,050 USA 2001-08-23