BigPatents India

Administering drug in the form of capsule formulation is a common practice. Capsule is in use for about 170 years. Right from its invention gelatine is the only material being used for the preparation of empty capsule although gelatin has many disadvatages. A process for the preparation of the hard capsule from ramarind seed polysaccharide has been developed to overcome the drawbacks. The process comprises the following steps; A) removing the testae from roasted tamarind seeds, pulverising the seed kernel and removing fat by soxhiation B) hydrolytic extraction of tamarind seed polysaccharide by boiling the kernal powder with 0.1 N HCL and recovering the polysaccharide by alocohol precipitation C) preparing aqueous solution having the polysaccharide , agar and glycerol D) casting the capsule by dipmoulding technique using separate mould pins for the body and cap E) removing the capsule shells from the pins , trimming the same and joining the body and cap.