METHODS FOR PRODUCTION OF AN ACTIVE INGREDIENT OF A DRUG OR A DIAGNOSTIC AGENT IN MDCK CELL SUSPENSION CULTURE
Application 475/KOLNP/2004 published 2006-04-14, filed 2004-04-08
The invention relates to methods for producing an active constituent of a pharmaceutical or a diagnostic agent, whereby (a) MDCK cells are infected with a virus, and (b) said MDCK cells are cultivated in a suspension culture on a technical scale and under conditions which enable viruses to multiply, the cultivation being carried out in a volume of at least 30 L. The invention also relates to methods for producing a pharmaceutical or a diagnostic agent, whereby an active constituent is produced according to one of the abovementioned methods and is mixed with a suitable adjuvant, auxiliary agent, buffer solution, diluting agent or pharmaceutical carrier. (FIG. NIL)
Applicant
CHIRON BEHRING GMBH & CO
Emil-von-Behring-Strasse 76, 35041 Marburg, Germany.
Inventor
VORLOP, Jürgen Frech, Christian LÜBBEN, Holger GREGERSEN, Jens-Peter
International Info
Classification: C12N 5/06
Publication Number: WO 03/023021
Application Date: 2002-09-11
Priority Information
101 44 906.2 Germany 2001-09-12