"HAPTEN-CARRIER CONJUGATES FOR TREATING AND PREVENTING NICOTINE ADDICTION"
Application IN/PCT/2001/00454/DEL published 2008-06-20, filed 2001-05-31
A nicotine hapten-carrier conjugate of the following formula useful in the management of nicotine addiction: wherein m is 1 to 2500, n is 0 to 12, y is 1 to 12, X is selected from the group consisting of NH-CO, CO-NH, CO-NH-NH, NH- NH-CO, NH-CO-NH, CO-NH-CO, and S-S; Y is selected from the group consisting of NH-CO, CO-NH, CO-NH-NH, NH- NH-CO, NH-CO-NH, CO-NH-NH-CO, and S-S, and the -(CH2 )n-X-(CH2)y - Y - moiety is bonded to the 3', 4' or 5' position of nicotine, and optionally the carrier protein is attached with a matrix such as herein described. No. of Pages : 48 No. of Claims : 11
Applicant
1)NABI
:12280 WILKINS AVENUE, ROCKVILLE, MARYLAND 20852, USA U.S.A.
Inventor
1)ENNIFAR, SOFIANE 2)FATTOM, ALI IBRAHIM 3)NASO, ROBERT B
International Info
Classification: A61K 47/48
Publication Number: WO 00/32239
Application Date: 1999-12-01
Priority Information
09/201,800 U.S.A. 1998-12-01